A2.3

Question of the Week

Infective endocarditis has an estimated incidence of 1.5 – 3.3 cases per 1000 IV drug users per year.  The risk appears to be augmented when the injected substance is which drug of abuse?  Why?

It is believed that cocaine carries a higher risk for endocarditis owing to the vasoconstrictive effects of the drug or the increased frequency of injection (NEJM, Vol. 353, pg. 1945)

Thank you for participating in this week’s Question of the Week.  Please check back soon for the next question.

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