The use of the metronidazole gel is not recommended for the treatment of vaginal trichomoniasis because of poor efficacy. Why is the topical form of the medication less efficacious?
Topically applied metronidazole gel is unlikely to achieve therapeutic levels in the urethra or perivaginal glands; therefore, use of the gel is not recommended. The CDC has published extensive guidelines for the treatment of STDs. Click here for a copy. See page 53 for the use of metronidazole in the treatment of trichomoniasis.
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